Agenda & Program Book

Welcome Remarks
Rebecca Baker (NIH HEAL Director)

Opening Remarks
Helene Langevin (NCCIH Director)
Historical Overview of Myofascial Pain Syndrome and Hypotheses

Session One - State of Science of Myofascial Pain Syndrome: Clinical Presentation, Pathophysiological Hypotheses, and Challenges
Chair- Michael Oshinsky (NINDS)
Co-chair- Leslie Derr (NIAMS)

Carla Stecco (University of Padova)
Fascial Anatomy, from Macro to Micro

Jay Shah (NIH/CC)
Chronic Myofascial Pain: Myogenic Considerations in its Pathogenesis and Clinical Manifestations

John Srbely (University of Guelph)
The Role of Neurogenic Mechanisms in the Pathophysiology and Clinical Manifestation of Chronic Myofascial Pain

David Lesondak (University of Pittsburgh)
A Clinician's Perspective on Treating Myofascial pain: Overview and Challenges

Mary Barbe (Temple University)
Basic Research/Animal Models Relevant to Myofascial Pain

BREAK

PANELIST COMMENTS

Lynn Gerber (George Mason University)
Kendi Hensel (Texas College of Osteopathic Medicine)
Eric Jacobson (Harvard Medical School)
Jan Mundo (Mundo Lifework)
Niki Munk (Indiana University)
Kathleen Sluka (University of Iowa)
Heather Tick (University of Washington)

PANEL DISCUSSION

QUESTIONS AND ANSWERS FROM THE ZOOM AUDIENCE AND VIDEOCAST AUDIENCE

VIRTUAL LUNCH

Session Two - Current Structural Imaging Approaches with Potential Application to Myofascial Pain Syndrome
Chair- Guoying Liu (NIBIB)
Co-chair- Merav Sabri (NCCIH)

Garry Gold (Stanford Schools of Engineering and Medicine)
Magnetic Resonance Imaging (MRI) Approaches with Potential Application to Myofascial Pain Syndrome

Bruce Damon (Vanderbilt University)
Quantitative MRI Methods with Potential Application to Myofascial Pain Syndrome

Sandip Biswal (Stanford University)
Use of Molecular Imaging and MR Neurography in the Identification of Peripheral Pain Generators

Siddhartha Sikdar (George Mason University)
From Qualitative to Quantitative Musculoskeletal Imaging for the Evaluation of Myofascial Tissues: Opportunities and Limitations

PANELIST COMMENTS

Christine Chung (University of California San Diego)
Bharti Khurana (Harvard Medical School)
Levon Nazarian (Thomas Jefferson University)
Antonio Stecco (NYU Langone Health)

PANEL DISCUSSION

QUESTIONS AND ANSWERS FROM THE ZOOM AUDIENCE AND VIDEOCAST AUDIENCE

BREAK

Session Three - Elastography Imaging Approaches with Potential Application to Myofascial Pain Syndrome
Chair- Helene Langevin (NCCIH)
Co-chair- Merav Sabri (NCCIH)

Kevin Parker (University of Rochester)
Ultrasound Elastography for Evaluation of Tissue Mechanical Properties

Helene Langevin (NCCIH)
Measurement of Shear Plane Tissue Mobility Using Ultrasound Elastography Techniques

Richard Ehman (Mayo Clinic College of Medicine and Science)
MR Elastography: Quantitatively Characterizing the Mechanical Properties of Skeletal Muscle and Myofascial Interfaces

PANELIST COMMENTS

Shigao Chen (Mayo Clinic Rochester)
Dieter Klatt (University of Illinois Chicago)
Neil Roberts (University of Edinburgh)
Sergio Sanabria (Stanford University School of Medicine)
Siddhartha Sikdar (George Mason University)
Robert Vining (Palmer College of Chiropractic)

PANEL DISCUSSION

QUESTIONS AND ANSWERS FROM THE ZOOM AUDIENCE AND VIDEOCAST AUDIENCE

WRAP UP

ADJOURN

Welcome Back
Jill Heemskerk (NIBIB Deputy Director)

Session Four - Emerging Promising Technologies for Myofascial Pain Syndrome: Electrophysiology, MRI, and PET
Chair- Alex Tuttle (NINDS)
Co-chair- Chuck Washabaugh (NIAMS)

Abhijit J. Chaudhari (University of California Davis)
Innovations in PET for Future Applications in Myofascial Pain Syndrome

Espen Spangenburg (East Carolina University)
Application of Techniques that Assess Physiological and Metabolic Parameters of Skeletal Muscle to Advance Our Understanding of Myofascial Pain Syndrome

Seward Rutkove (Beth Israel Deaconess Medical Center, Harvard)
Electrophysiology Techniques and Potential Applications for Myofascial Tissues

Els Fieremans (NYU Langone Health)
In Vivo Imaging of Tissue and Muscle Microstructure

PANELIST COMMENTS

Vania Apkarian (Northwestern University)
Mark Does (Vanderbilt University)
Jordi Serra (King's College Hospital, London)
Samuel Ward (University of California San Diego)

PANEL DISCUSSION

QUESTIONS AND ANSWERS FROM THE ZOOM AUDIENCE AND VIDEOCAST AUDIENCE

BREAK

Session Five - Emerging Promising Technologies for Myofascial Pain Syndrome: Tissue Engineering, Artificial Intelligence, and Computational Modeling
Chair- Yolanda Vallejo (NIDCR)
Co-chair- Theresa Cruz (NICHD/NCMRR)

Jeffrey Lotz (University of California San Francisco)
Quantifying Associations Between Paraspinal Muscle Quality, Spinal Pathologies, and Skeletal Biomechanics

Sharmila Majumdar (University of California San Francisco)
The Role of Machine Learning for Muscle Segmentation and Characterization of Muscle Properties

Silvia Blemker (University of Virginia)
Multi-scale Computational Modeling Integrates Biology and Mechanics to Prove New Insights into Muscle Dysfunction

Hai Yao (Clemson, Medical University of South Carolina)
Integrating Multimodality Measurement and Multiscale Modeling to Assess Temporomandibular Disorders

PANELIST COMMENTS

Lucia Cevidanes (University of Michigan)
Adam Hantman (Janelia Research Campus)
Lealem Mulugeta (InSilico Labs, LLC and Medalist Performance)
Thomas Myers (University of Rochester)

PANEL DISCUSSION

QUESTIONS AND ANSWERS FROM THE ZOOM AUDIENCE AND VIDEOCAST AUDIENCE

VIRTUAL LUNCH

Session Six - General Discussion
Chair- Wen Chen (NCCIH)
Co-chair- Dena Fischer (NIDCR)

PANELIST COMMENTS

Allan Basbaum (University of California San Francisco)
Christine Chung (University of California San Diego)
Bill Maixner (Duke University)
Julie Fritz (The University of Utah)
Daniel Sodickson (NYU Langone Health)

PANEL DISCUSSION

Summary and Concluding Remarks
Helene Langevin (NCCIH Director)

ADJOURN